Quantcast
Channel: DR ANTHONY MELVIN CRASTO Ph.D – All About Drugs
Viewing all articles
Browse latest Browse all 823

Benzisoxazole: a privileged scaffold for medicinal chemistry

$
0
0

 

Med. Chem. Commun., 2017, Advance Article
DOI: 10.1039/C7MD00449D, Review Article
K. P. Rakesh, C. S. Shantharam, M. B. Sridhara, H. M. Manukumar, Hua-Li Qin
The benzisoxazole analogs represent one of the privileged structures in medicinal chemistry and there has been an increasing number of studies on benzisoxazole-containing compounds.

Benzisoxazole: a privileged scaffold for medicinal chemistry

 

Abstract

The benzisoxazole analogs represent one of the privileged structures in medicinal chemistry and there has been an increasing number of studies on benzisoxazole-containing compounds. The unique benzisoxazole scaffold also exhibits an impressive potential as antimicrobial, anticancer, anti-inflammatory, anti-glycation agents and so on. This review examines the state of the art in medicinal chemistry as it relates to the comprehensive and general summary of the different benzisoxazole analogs, their use as starting building blocks of multifarious architectures on scales sufficient to drive human drug trials. The number of reports describing benzisoxazole-containing highly active compounds leads to the expectation that this scaffold will further emerge as a potential candidate in the field of drug discovery.

Hua-Li Qin

Dr. Hua-Li Qin Ph. D 2009
qinhuali@bu.edu

Department of Pharmaceutical Engineering, School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan, PR China

  • Wuhan University of Technology

Hua-Li joined the Panek group in 2005.

C. S. Shantharam at Pooja Bhagavat Memorial Mahajana P.G Centre

C. S. Shantharam

M.Sc., Ph.D
Assistant professor
Pooja Bhagavat Memorial Mahaja… , Mysore · Department of Chemistry
Department of Chemistry, Pooja Bhagavath Memorial Mahajana Education Centre, Mysuru-570016, India
Image result for Department of Chemistry, Pooja Bhagavat Memorial Mahajana Education Centre, Mysore-570016, India
Image result for Department of Chemistry, Pooja Bhagavat Memorial Mahajana Education Centre, Mysore-570016, India

Hua-Li Qin

 

Manukumar H M at University of Mysore

Manukumar H M

Master of Science
Research Scholar

 

////////////Benzisoxazole, scaffold, medicinal chemistry

Share


Viewing all articles
Browse latest Browse all 823

Trending Articles