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BMS 919373
Share: . Bethany Halford on Twitter: “BMS-919373, from $BMS for …https://twitter.com/beth_halford/status/634105343719682048 Aug 19, 2015 – BMS–919373, from $BMS for atrial fibrillation #ACSBoston MEDI...
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Continuous-Flow Process for the Synthesis of m-Nitrothioanisole
Share: A continuous-flow process for the preparation of m-nitrothioanisole has been set up. The starting material m-nitroaniline was diazotized to give diazonium chloride, followed by azo-coupling with...
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GDC-0084
Share: GDC-0084 CAS#: 1382979-44-3 Chemical Formula: C18H22N8O2 Exact Mass: 382.1866 Synonym: RG7666; RG-7666; RG 7666; GDC-0084; GDC0084; GDC 0084. IUPAC/Chemical Name:...
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The new Annex 16 “Certification by a Qualified Person and Batch Release” will...
Share: The new Annex 16 is coming into Force The new Annex 16 “Certification by a Qualified Person and Batch Release” will become effective as of 15 April 2016. The contents will reflect the coming...
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ICH Q3D implemented in the European Pharmacopoeia: Revision of Two General...
Share: ICH Q3D implemented in the European Pharmacopoeia: Revision of Two General Monographs with Regard to Elemental Impurities Two general monographs of the European Pharmacopoeia have been revised...
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DS 2330 by Daiichi Sankyo
Share: DS 2330 4-[2-(4-{[2-({3-[(trans-4-carboxy-cyclohexyl)(ethyl)sulfocarbamoyl]benzoyl}amino)-5-(piperidin-1-yl)benzoyl]amino}phenyl)ethyl]benzoic acid, 4- [2- (4 – {[2 – ({3 –...
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Curis and Aurigene’s CA 4948, AU 4948
Share: CA 4948, AU 4948,AU-4948, CA-4948 STRUCTURE AND SYNTHESIS COMING…….. Company Aurigene Discovery Technologies Ltd. Description Oral IL-1 receptor-associated kinase 4 (IRAK4) inhibitor Molecular...
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Curis and Aurigene’s AUPM 170, CA 170
Share: 1,2,4-oxadiazole and 1 ,2,4-thiadiazole compounds of formula (I): ONE EXAMPLE OR 1,3,4-oxadiazole and 1 ,3,4-thiadiazole compounds of formula (I): EXAMPLES PREDICTED AUPM 170, CA 170,...
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ND 2158
Share: (2S)-2-hydroxy-3-[(3R)-12-{[(1r,4r)-4-(morpholin-4-yl)cyclohexyl]oxy}-7-thia-9,11-diazatricyclo[6.4.0.0²,⁶]dodeca-1(12),2(6),8,10-tetraen-3-yl]propanamide...
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ND 2110
Share: ND -2110 Molecular Formula: C21H28N4O3S Molecular Weight: 416.53702 g/mol...
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CN-128 for the treatment of thelassemia and iron overload
Share: CN-128 (R)-3-Hydroxy-1-(1-hydroxy-3-benzyl propyl-2-)2-methyl pyridine-4(1H)-one IND Filing CN-128 is potentially for the treatment of thelassemia and iron overload. Zhejiang University, 浙江大学...
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Debiopharm and Aurigene dual c-src / jak inhibitors
Share: Debio 1142 Jak2 tyrosine kinase inhibitor; Src tyrosine kinase inhibitor...
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PF-05387552
Share: PF-05387552 IRAK4 CAS 1604034-71-0 C25 H27 N5 O2 11H-Indolo[3,2-c]quinoline-9-carbonitrile, 2-methoxy-3-[3-(4-methyl-1-piperazinyl)propoxy]-...
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FDA approves new drug Venclexta (venetoclax) for chronic lymphocytic leukemia...
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Etamicastat
Share: Etamicastat HCl salt CAS: 677773-32-9 (HCl salt) CAS 760173-05-5 (free base). Chemical Formula: C14H16ClF2N3OS Molecular Weight: 347.8088 Synonym: BIA 5-453; BIA5-453; BIA-5-453; Etamicastat...
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Zamicastat
Share: CAS 1080028-80-3 BASE 1383828-47-4 OF HCL SALT C21 H21 F2 N3 O S BASE 2H-Imidazole-2-thione,...
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Asvasiran sodium (ALN-RSV01)
Share: RNA, (C-U-U-G-A-C-U-U-U-G-C-U-A-A-G-A-G-C-C-DT-DT), COMPLEX WITH RNA (G-G-C-U-C-U-U-A-G-C-A-A-A-G-U-C-A-A-G-DT-DT) Duplex of...
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AMG 337
Share:. PIC CREDIT.BETHANY HALFORD Name: AMG-337(AMG337; AMG 337) Cas 1173699-31-4 Formula: C23H22FN7O3 M.Wt: 463.46 Chemical Name:...
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INCB24360 (epacadostat)
Share: Epacadostat (Z)-N-(3-bromo-4-fluorophenyl)-N’-hydroxy-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole-3-carboxamidine 1,2,5-Oxadiazole-3-carboximidamide,...
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PF-06260414
Share: PF-06260414 CAS: 1612755-71-1 Chemical Formula: C14H14N4O2S Exact Mass: 302.0837 PF-06260414; PF 06260414; PF06260414; PF6260414; PF-6260414; PF 6260414. IUPAC/Chemical Name:...
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