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TEZACAFTOR, VX 661 for treatment of cystic fibrosis disease.
Share: TEZACAFTOR, VX 661 CAS : 1152311-62-0; Molecular FormulaC26H27F3N2O6 Average mass520.498 Da...
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OSILODROSTAT for Treatment of Cushing’s Syndrome
Share: OSILODROSTAT LCI 699, LCI 699NX Novartis Ag INNOVATOR UNII-5YL4IQ1078, CAS 928134-65-0 Benzonitrile, 4-[(5R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl]-3-fluoro-...
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Multicomponent reactions: A simple and efficient route to heterocyclic...
Share:. Multicomponent reactions: A simple and efficient route to heterocyclic phosphonates Mohammad Haji Beilstein J. Org. Chem. 2016, 12, 1269–1301. published 21 Jun 2016 Chemistry Department,...
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Stereoselective synthesis of tricyclic compounds by intramolecular...
Share:. Stereoselective synthesis of tricyclic compounds by intramolecular palladium-catalyzed addition of aryl iodides to carbonyl groups Freie Universität Berlin, Institut für Chemie und Biochemie,...
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Besifloxacin hydrochloride (Besivance)
Share: Besifloxacin SS 734, BOL 303224A, ISV-403 MW 430.301, MF C19H21ClFN3O3 141388-76-3 CAS 7-[(3R)-3-aminoazepan-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid...
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Cipla to invest in South Africa’s first biosimilars production facility
Share: Cipla to invest in South Africa’s first biosimilars production facility Indian-based pharmaceutical and biotechnology company Cipla will invest more than R1.3bn ($19.34m) in the first advanced...
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EMA reviews Medicines manufactured at U.S. Company
Share: Following the issuance of two Non-Compliance Reports for two sites of the US based company, EMA has started a review of medicines manufactured by Pharmaceutics International Inc., USA. The...
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Drafts of revised USP plastic packaging chapters and : removal of the...
Share: In a recent Pharmacopeial Forum two revised USP general chapters have been published for comment. With these drafts, the USP expert committee is removing the requirement for <87>...
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EDQM announces revision of general chapter Monocyte Activation Test (2.6.30)
Share: On 23 June, the EDQM in Strasbourg announced the revision of the pharmacopoeial general chapter 2.6.30 on Monocyte Activation Test. see...
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NEW PATENT, WO 2016108172, OSPEMIFENE AND FISPEMIFENE, OLON S.P.A.
Share: Ospemifene is useful for treating menopause-induced vulvar and vaginal atrophy; while fispemifene is useful for treating symptoms related with male androgen deficiency and male neurological...
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Photochemical Rearrangement of Chiral Oxaziridines in Continuous Flow:...
Share: A method for synthesizing chiral lactams from chiral oxaziridines in continuous flow is described. The oxaziridines are readily available from cyclic ketones. Photolysis of the oxaziridines...
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Chemistry in Water
Share: Chemistry in Water 1 Isley et al. reported the use of the nonionic amphiphile TPGS-750-M (2 wt %) in water to facilitate nucleophilic aromatic substitution reactions (SNAr) with oxygen,...
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RG 6080
Share: RG-6080 Sulfuric acid, mono[(1R,2S,5R)-2-[[(2-aminoethoxy)amino]carbonyl]-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester Phase I A β-lactamase inhibitor potentially for the...
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Sreeni Labs Private Limited, Hyderabad, India ready to deliver New,...
Share: Sreeni Labs Private Limited, Hyderabad, India is ready to take up challenging synthesis projects from your preclinical and clinical development and supply from few grams to multi-kilo...
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New Patent, WO 2016110874, Artemisinin , IPCA Laboratories Ltd
Share: New Patent, WO 2016110874, Artemisinin , IPCA Laboratories Ltd FOR Cancer; Parasitic infection; Plasmodium falciparum infection; Viral infection WO-2016110874 KUMAR, Ashok; (IN). SINGH,...
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WO 2016110798, Piramal Enterprises Ltd, New Patent, Lurasidone
Share: Lurasidone – it having been developed and launched by Sumitomo Dainippon Pharma. Lurasidone was launched for schizophrenia in the US by Sumitomo’s US subsidiary Sunovion Pharmaceuticals. WO...
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Doravirine, MK-1439
Share: Doravirine, MK-1439……….. AN ANTIVIRAL 3-Chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2-dihydro-3-pyridinyl}oxy)benzonitrile Benzonitrile,...
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New Warning Letter of the FDA with the Focus on “Data Integrity”
Share: The FDA has set the focus of its inspections on data integrity for quite some time already. The most recent Warning Letter addressed to a Chinese API manufacturer dated August 2016 clearly...
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New Q&A Document on the Visual Inspection of Parenterals available
Share: The ECA’s Visual Inspection Group has developed a new document with answers to frequently asked questions. This new Q&A document is now available for download on the Group’s website. Read...
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Shamisha Resource Managment, Experts in Recruitment, Pharmaceutical and FMCG...
Share: They specialise in Recruitment service in Food/FMCG/ Pharma, with offices in Ahmedabad and Mumbai .We have track record of accurate and prompt service in most ethical manner. I happen to be a...
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