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Channel: DR ANTHONY MELVIN CRASTO Ph.D – All About Drugs
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1H-1H COSY NMR

www.simplesharebuttons.comShare:1H-1H COSY (COrrelated SpectroscopY) is a useful method for determining which signals arise from neighboring protons (usually up to four bonds). Correlations appear when...

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2D NMR spectroscopy for the structural elucidation of 4.

www.simplesharebuttons.comShare: A multistep single-crystal-to-single-crystal bromodiacetylene dimerization http://www.nature.com/nchem/journal/v5/n4/fig_tab/nchem.1575_F6.html Tobias N. Hoheisel,...

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Sucrose 2D NMR Spectra

www.simplesharebuttons.comShare:Sucrose 2D NMR Spectra The sugar sucrose can be used to illustrate  homonuclear 2D NMR experiment: the TOCSY. Sucrose Table sugar Sucrose (“table sugar”) is a...

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Relugolix (TAK-385) in phase 2 By Takeda for the treatment of endometriosis...

www.simplesharebuttons.comShare: Relugolix (TAK-385)...

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LM11A-31-BHS….. (2S,3S)-2-amino-3-methyl-N-(2-morpholinoethyl)-pentanamide

www.simplesharebuttons.comShare:    LM11A-31-BHS (2S,3S)-2-amino-3-methyl-N-(2-morpholinoethyl)-pentanamide 2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]-pentanamide dihydrochloride CAS Number...

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Cabotegravir, GSK 744 IN PHASE 2 FOR HIV INFECTION

www.simplesharebuttons.comShare: Cabotegravir, GSK 744, (3S,11aR)-N-(2,4-Difluorobenzyl)-6-hydroxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydro[1,3]oxazolo[3,2-a]pyrido[1,2-d]pyrazine-8-carboxamide 3S,...

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Nanotechnology Drug Delivery Systems: An Insight

www.simplesharebuttons.comShare: Nanosponge particle attaches to Human Breast Cancer cells One of the most important applications of nanotechnology in medicine involves use of nanoparticles to deliver...

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Blinged-Out Fat Blob Nanotrucks for Targeted Drug Delivery

www.simplesharebuttons.comShare:   Targeted drug delivery is a popular area of research that melds together the disciplines of chemistry, medicine, and materials. The basic idea is to develop ways to...

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Cerecor’s selective NMDA receptor subunit 2B antagonist CERC-301 (MK-0657)...

www.simplesharebuttons.comShare: CERC-301 (MK-0657) MK-657, c-6161, AGN-PC-00887R structure source….http://www.google.com/patents/WO2013156614A1?cl=en    my id is amcrasto@gmail.com Treat depression;...

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Boston Scientists Develop New Probiotic Supplement to Manage Weight

www.simplesharebuttons.comShare: (Boston) – Healthcare experts continue to regard probiotics as one of the most powerful tools in the management of everything from constipation and bloating to diarrhea...

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The role of modern drug discovery in the fight against neglected and tropical...

www.simplesharebuttons.comShare:The role of modern drug discovery in the fight against neglected and tropical diseases Med. Chem. Commun., 2014, Advance Article DOI: 10.1039/C4MD00011K, Review Article...

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A highly efficient and recyclable ligand-free protocol for the Suzuki...

www.simplesharebuttons.comShare:A highly efficient and recyclable ligand-free protocol for the Suzuki coupling reaction of potassium aryltrifluoroborates in water Green Chem., 2014, 16,2185-2189 DOI:...

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Nanoparticles Deliver Three Cancer Drugs To Tumors Drug Delivery: Polymeric...

www.simplesharebuttons.comShare: CANCER KILLER A drug-delivering nanoparticle with cisplatin core (green) is formed by polymerization of doxorubicin- and camptothecin-derivatized monomers and a...

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One-Two Nanopunch For Difficult-To-Treat Breast Cancer Drug Delivery: Layered...

www.simplesharebuttons.comShare: Double Duty To deliver a one-two nanopunch to triple-negative breast cancer tumors, researchers start with a lipid-coated sphere filled with the chemotherapy drug...

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Academic−Industrial Partnerships in Drug Discovery and Development

www.simplesharebuttons.comShare: Author: Jonathan Faiz Published: 22 April 2014 Copyright: Wiley-VCH Verlag GmbH & Co. KGaA Source / Publisher: Angewandte Chemie International Edition Associated...

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More and more companies are using fragment-based lead design as a drug...

www.simplesharebuttons.comShare: shaking hands Small fragments that bind in nearby pockets can be connected to make a lead. In the pursuit of new pharmaceuticals, many medicinal chemists want to start...

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MIT chemists design nanoparticles that can deliver three cancer drugs at a time.

www.simplesharebuttons.comShare:  Targeting Cancer with a Triple Threat | MIT Technology Review MIT chemists design nanoparticles that can deliver three cancer drugs at a time. Delivering chemotherapy...

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5 Things You Should Know About MERS, The Deadly Virus That’s Now Breaking Out...

www.simplesharebuttons.comShare: The MERS virus. MERS (Middle Earth Respiratory Virus) A new spike in cases of a deadly respiratory virus, in Saudi Arabia and the United Arab Emirates, is prompting new...

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Europe green light for GSK COPD drug Incruse (umeclidinium)

www.simplesharebuttons.comShare: Regulators in Europe have given the green light to GlaxoSmithKline’s new chronic obstructive pulmonary disease drug Incruse. Specifically, the European Commission has...

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Otsuka multi-drug resistant TB drug approved in Europe

www.simplesharebuttons.comShare: Delamanid Otsuka Pharmaceutical Co has been given the green light to sell its tuberculosis drug Deltyba in Europe. Read more at:...

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