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RUFINAMIDE….FLOW SYNTHESIS
www.simplesharebuttons.comShare: A report (Org Process Res Dev 2014, ASAP article) out of Jamison’s group at MIT, provides a 3-step synthesis of Rufinamide in 92% overall yield. The process illustrates...
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Synthesis of Methoxyisopropyl (MIP)-Protected (R)-Mandelonitrile and...
www.simplesharebuttons.comShare: Cyanohydrins are synthetically versatile chiral building blocks in organic synthesis. They can be conveniently synthesized in enantiomerically pure form via...
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Oleocanthal for treating pain
www.simplesharebuttons.comShare:“Oleocanthal” is specifically deacetoxydialdehydic ligstroside aglycone, which exists as a single isomer (enantiomer). The (-)-enantiomer is the natural product and has...
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Diastereoselective [2+2] Photocycloaddition of a Chiral Cyclohexenone with...
www.simplesharebuttons.comShare: The diastereoselective [2+2] photocycloaddition of ethylene to a chiral cyclohexenone was studied in a continuous flow microcapillary reactor. In all cases examined,...
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A monolith immobilised iridium Cp* catalyst for hydrogen transfer reactions...
www.simplesharebuttons.comShare: http://pubs.rsc.org/en/Content/ArticleLanding/2015/OB/C4OB02376E#!divAbstract A monolith immobilised iridium Cp* catalyst for hydrogen transfer reactions under flow...
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Tipifarnib
www.simplesharebuttons.comShare: 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone; (R)-(+)-R 115777; Zarnestra; 192185-68-5 zarnestra,...
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Scaling from Milligrams to 1-2Kg
www.simplesharebuttons.comShare: Dr John Knight Scaling from Milligrams to 1-2Kg see...
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Methohexital
www.simplesharebuttons.comShare: Methohexital or methohexitone, (marketed under the brand name Brevital) is a drug which is a barbiturate derivative. It is classified as short-acting, and has a rapid...
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Saudi Patent Office AND GULF ( GCC Patent office)
www.simplesharebuttons.comShare: http://www.gccpo.org/DefaultEn.aspx The Patent Office of the Cooperation Council for the Arab States of the Gulf is delighted to announce launching the electronic...
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Overview of the Patent System in Korea
www.simplesharebuttons.comShare: South Korea http://www.kipo.go.kr/kpo/user.tdf?a=user.english.main.BoardApp&c=1001 The Korean Intellectual Property Office (KIPO) is the patent office and...
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TRIPS Agreement
www.simplesharebuttons.comShare: WTO members (where the TRIPS agreement applies) Parties to the Agreement where also the membership of the European Union applies “TRIPS” redirects here. For the...
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IMPROVING CHEMICAL SYNTHESIS USING FLOW REACTORS.
www.simplesharebuttons.comShare: Improving chemical synthesis using flow reactors. Expert Opin Drug Discov Expert Opin Drug Discov 2007 Nov;2(11):1487-503 Charlotte Wiles, Paul Watts Charlotte...
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Synthetic chemistry fuels interdisciplinary approaches to the production of...
www.simplesharebuttons.comShare: 7 Semi-synthesis of artemisinin using continuous flow. The Seeberger group has recently developed a continuous flow approach to the production of … In the developing...
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Cobalt-Catalyzed C–H Cyanation of (Hetero)arenes and 6-Arylpurines with...
www.simplesharebuttons.comShare: Cobalt-Catalyzed C–H Cyanation of (Hetero)arenes and 6-Arylpurines with N-Cyanosuccinimide as a New Cyanating Agent http://pubs.acs.org/doi/abs/10.1021/ol503680d Amit...
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What is a chemical synthesis pharmaceutical plant?
www.simplesharebuttons.comShare: Manufacturing process for chemical synthesis pharmaceuticals There are two main types of processes used to manufacture pharmaceuticals: chemical synthesis based on...
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A Burst of Aroma Light-induced generation of gas breaks open microcapsules...
www.simplesharebuttons.comShare: A Burst of Aroma Light-induced generation of gas breaks open microcapsules and releases fragrances Fragrances that are sensitive or need to be released with a time...
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What is 35 U.S. Code § 112 – Specification, ………..it is so easy to understand,...
www.simplesharebuttons.comShare: click U.S. Code› Title 35 › Part II › Chapter 11 › § 112………explanation see below Law is easy, …. learn with me and explained by cornell I picked...
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A Green and Sustainable Approach: Celebrating the 30th Anniversary of the...
www.simplesharebuttons.comShare:A Green and Sustainable Approach: Celebrating the 30th Anniversary of the Asymmetric l-Menthol Process Takasago has been devoted to producing l-menthol since 1954, and...
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Large-Scale Continuous Flow Transformation of Oximes into Fused-Bicyclic...
www.simplesharebuttons.comShare: Here, we report a continuous flow protocol for the [3 + 2] cycloaddition of nitrones, in situ generated from oximes, into bicyclic isoxazolidines. This thermal process...
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