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Channel: DR ANTHONY MELVIN CRASTO Ph.D – All About Drugs
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DEXAMETHASONE

www.simplesharebuttons.comShare:  -alpha-fluoro-11-beta,17-alpha,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione; 9-alpha-fluoro-16-alpha-methylprednisolone;...

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QUININE

www.simplesharebuttons.comShare: Quinine Molecular Formula: C20H24N2O2 Molecular Weight: 324.417   IUPAC Name: 6′-Methoxycinchonan-9-ol CAS Number: 56-54-2 PubChem: 1065 NMRShiftDB: 10016314...

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A route to convert CO2: synthesis of 3,4,5-trisubstituted oxazolones

www.simplesharebuttons.comShare:     Green Chem., 2015, Advance Article DOI: 10.1039/C4GC02033B, Paper Jiayin Hu, Jun Ma, Zhaofu Zhang, Qinggong Zhu, Huacong Zhou, Wenjing Lu, Buxing Han CO2 can react...

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Pimobendan

www.simplesharebuttons.comShare:   Pimobendan CAS: 74150-27-9 3-[2-(4-methoxyphenyl)-3H-benzimidazol-5-yl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one...

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SPIN SPIN COUPLING

www.simplesharebuttons.comShare:The source of spin-spin coupling The 1H-NMR spectra that we have seen so far (of methyl acetate and para-xylene) are somewhat unusual in the sense that in both of these...

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Which Pharmas Spend the Most on R&D?

www.simplesharebuttons.comShare: Which Pharmas Spend the Most on R&D? Pharmas and biotechs have spent $1 trillon on R&D over the last decade. By Kathlyn Stone Pharma Expert...

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New novel method to twist molecule

www.simplesharebuttons.comShare: The new helical molecule (right) was due to the different length strands (blue and gray) a spatial arrangement of a (schematized in the middle), similar to the railing...

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Evaluation of antispasmodic activity of different Shodhit guggul using...

www.simplesharebuttons.comShare:   Evaluation of antispasmodic activity of different Shodhit guggul using different shodhan process Rachana Kamble, Sadhana Sathaye, DP Shah University Institute of...

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RABEPRAZOLE SPECTRAL VISIT

www.simplesharebuttons.comShare:                   1H NMR RABEPRAZOLE RAB standard: (DMSOd6 400 MHz) δ 8.28 (d, 1H, J=5.56 Hz), 7.46 (m, 2H), 6.93 (d, 1H, J=5.68 Hz), 6.88 (m, 2H), 4.57 (AB, 2H,...

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Dithiocarbamates: Reagents for the Removal of Transition Metals from Organic...

www.simplesharebuttons.comShare: Dithiocarbamates: Reagents for the Removal of Transition Metals from Organic Reaction Media http://pubs.acs.org/doi/abs/10.1021/op500336h William P. Gallagher * and Anh...

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Lexipafant

www.simplesharebuttons.comShare:    Lexipafant CAS : 139133-26-9  N-Methyl-N-[[4-[(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)methyl]phenyl]sulfonyl]-L-leucine ethyl ester...

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Arterolane maleate a Ranbaxy NCE set to conquer Malaria

www.simplesharebuttons.comShare: Arterolane cas 664338-39-0, UNII-3N1TN351VB, OZ277, RBX-11160, NCGC00274173-01 Molecular Formula: C22H36N2O4  Molecular Weight: 392.53224 Medicines For Malaria Venture...

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(S)-(+)-3-HYDROXY-2,2-DIMETHYLCYCLOHEXANONE

www.simplesharebuttons.comShare:       (S)-(+)-3-hydroxy-2,2-dimethylcyclohexanone bp 85–87°C at 3.7 mm, [α]21D + 23.0° (CHCl3, c 2.0) The spectral properties of...

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Piece by Piece A guide to fragment-based drug discovery

www.simplesharebuttons.comShare: DESIGNING A BETTER DRUG: The combination of chemical groups from three different fragments that bind weakly to an enzyme produce a potent new enzyme inhibitor (center)...

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5-hydroxy-4-keto-pentenoic acid (HKPA).

www.simplesharebuttons.comShare:   C. Oliver Kappe, University of Graz, Austria, and colleagues prepared for the first time the potential new platform molecule H2MF in pure form and converted it to the...

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CMI 977, LDP 977

www.simplesharebuttons.comShare: CMI 977 C16-H19-F-N2-O4 322.3341 Millennium (Originator), Taisho (Licensee) (2S,5S)-1-[4-[5-(4-Fluorophenoxymethyl)tetrahydrofuran-2-yl]-3-butynyl]-1-hydroxyurea...

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Ensuring Process Stability with Reactor Temperature Control Systems

www.simplesharebuttons.comShare: Temperature control plays an important role in industrial processes, pilot plants, and chemical and pharmaceutical laboratories. When controlling reactors, both...

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ANTIMALARIAL PIPELINE

www.simplesharebuttons.comShare:   Malaria, a devastating infectious disease caused by Plasmodium spp., leads to roughly 655,000 deaths per year, mostly of African children. To compound the problem,...

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An Integrated Synthesis–Purification System to Accelerate the Generation of...

www.simplesharebuttons.comShare: An Integrated Synthesis–Purification System to Accelerate the Generation of Compounds in Pharmaceutical Discovery...

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Meclinertant (SR48692)

www.simplesharebuttons.comShare:      2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]adamantane-2-carboxylic acid Meclinertant (SR-48692) is a drug which acts as a...

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