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EU GMP Annex 1 Revision 2016 – what does the pharmaceutical industry expect?
Share: Dr Friedrich Haefele, Vice President Fill & Finish Biopharma at Boehringer Ingelheim Dr Friedrich Haefele, Vice President Fill & Finish Biopharma at Boehringer Ingelheim talked in his...
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Crisil rings warning bell for pharma on US slowdown
Share: Companies like Dr. Reddy’s Laboratories and Sun Pharma derive close to 60% of their revenue from exports to the US. Lupin too, gets 45% of its revenue from generic formulation sales to the US,...
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SETIPIPRANT
Share: Setipiprant, KYTH-105 CAS 866460-33-5 2-(2-(1-naphthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetic acid...
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Flow synthesis of Fluoxetine
Share: Scheme 1: Flow synthesis of fluoxetine (46). PIC CREDIT, The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry, Marcus Baumann and Ian R. Baxendale,...
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Flow approach towards AZD 6906
Share: Scheme 1: Flow approach towards AZD6906 (65). PIC CREDIT, The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry, Marcus Baumann and Ian R. Baxendale,...
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FDA approves new diagnostic imaging agent FLUCICLOVINE F-18 to detect...
Share: FLUCICLOVINE F-18 Cyclobutanecarboxylic acid, 1-amino-3-(fluoro-18F)-, trans- [ Molecular FormulaC5H818FNO2 Average mass132.124 Da Axumin (fluciclovine F 18) fluciclovinum (18F) GE-148 NMK36...
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[F-18](2S,4S)-4-(3-Fluoropropyl)glutamine
Share: [F-18](2S,4S)-4-(3-Fluoropropyl)glutamine CAS 1196963-79-7 MF C8 H15 F N2 O3 Heptanoic acid, 2-amino-4-(aminocarbonyl)-7-(fluoro-18F)-, (2S,4S)- [18F](2S,4S)-4-FPGln...
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Rovatirelin Hydrate
Share: Rovatirelin Hydrate, S-0373, Rovatirelin, RN: 204386-76-5 UNII: 9DL0X410PY...
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Difelikefalin
Share: Difelikefalin, CR-845; MR-13A-9; MR-13A9 4-amino-1- (D-phenylalanyl-D-phenylalanyl-D-leucyl-D-lysyl) piperidine-4-carboxylic acid Phase III C36H53N7O6, 679.40573 Originator Ferring...
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[18F]AMG 580
Share: [18F]AMG 580 CAS 1879904-74-1 MF C26 H24 F N5 O3 NOTE………CAS OF AMG 580 IS 1227067-71-1, WITHOUT 18F AMG 580...
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GSK 6853
Share: GSK 6853 CAS 1910124-24-1 C22 H27 N5 O3, 409.48 Benzamide, N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxy- (R)-N-(1...
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Targeted Nanoparticles for the Delivery of Novel Bioactive Molecules to...
Share: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with poor prognosis and limited therapeutic options. Therefore, there is an urgent need to identify new, safe, and targeted...
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CCT 245737
Share: CCT 245737 CAS:1489389-18-5 M.Wt: 379.34 Formula: C16H16F3N7O 2-Pyrazinecarbonitrile, 5-[[4-[[(2R)-2-morpholinylmethyl]amino]-5-(trifluoromethyl)-2-pyridinyl]amino]-...
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Self-optimisation of the final stage in the synthesis of EGFR kinase...
Share: React. Chem. Eng., 2016, Advance Article DOI: 10.1039/C6RE00059B, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Nicholas Holmes,...
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Intensified biocatalytic production of enantiomerically pure...
Share: Catal. Sci. Technol., 2016, Advance Article DOI: 10.1039/C6CY00855K, Communication Nicholas J. Weise, Syed T. Ahmed, Fabio Parmeggiani, Elina Siirola, Ahir Pushpanath, Ursula Schell, Nicholas J....
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Mechanisms and reactivity differences of proline-mediated catalysis in water...
Share: Catal. Sci. Technol., 2016, 6,3378-3385 DOI: 10.1039/C6CY00033A, Paper Gang Yang, Lijun Zhou Several key issues regarding the mechanisms of proline catalysis are unravelled by first-principles...
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Activated nanostructured bimetallic catalysts for C-C coupling reactions:...
Share: Catal. Sci. Technol., 2016, 6,3341-3361 DOI: 10.1039/C5CY02225H, Minireview Rohit Kumar Rai, Deepika Tyagi, Kavita Gupta, Sanjay Kumar Singh This minireview highlights the recent progress made...
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Дапипразол Dapiprazole
Share: Dapiprazole CAS 72822-12-9 HCL SALT 72822-13-0 5,6,7,8-Tetrahydro-3-(2-(4-(O-tolyl)-1-piperazinyl)ethyl)-S-triazolo(4,3-a)pyridine Dapiprazole (Rev-Eyes) is an alpha blocker. It is used to...
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EDQM’s new Guideline on Electronic Submissions for CEP Applications
Share: EDQM’s new Guideline on Electronic Submissions for CEP Applications As of today (June, 1st 2016), the EDQM doesn’t accept any CEP application in paper format. Read more here about the structure...
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Results of a Survey on ICH Q3D “Elemental Impurities”
Share: For most companies manufacturing APIs and pharmaceutical products, the implementation of ICH Q3D has a serious impact – as shown in a survey recently carried out by the ECA. Read more about the...
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