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Teslaphoresis of Carbon Nanotubes
Share: This paper introduces Teslaphoresis, the directed motion and self-assembly of matter by a Tesla coil, and studies this electrokinetic phenomenon using single-walled carbon nanotubes (CNTs)....
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Solvates, Salts, and Cocrystals: A Proposal for a Feasible Classification System
Share: The design of pharmaceutical cocrystals has initiated widespread debate on the classification of cocrystals. Current attempts to classify multicomponent crystals suffer from ambiguity, which has...
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Optimization, Production, and Characterization of a...
Share: We have synthesized and characterized a novel phosphorothioate CpG oligodeoxynucleotide (CpG ODN)-Ficoll conjugated nanoparticulate adjuvant, termed DV230-Ficoll. This adjuvant was constructed...
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BMS-520, a Potent and Selective Isoxazole-Containing S1P1 Receptor Agonist
Share: BMS-520 CAS: 1236188-38-7 MF: C23H17F3N4O4 MW: 470.1202 Synonym: BMS-520; BMS 520; BMS520. INNOVATOR Bristol-Myers Squibb Company INVENTORS Scott Hunter Watterson, Alaric J. Dyckman,William J....
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ICH Q3D Implementation Working Group (IWG)—Training Modules
Share: ICH Q3D Implementation Working Group (IWG)—Training Modules ICH Q3D is a complex guideline. The overall requirement in terms of control is clear—there are defined limits for some 24 elements,...
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MK-7145
Share: MK-7145, cas 1255204-84-2 1(3H)-Isobenzofuranone, 5,5′-(1,4-piperazinediylbis((1R)-1-hydroxy-2,1-ethanediyl))bis(4-methyl- MF C26 H30 N2 O6, Molecular Weight 466.53 1(3H)-Isobenzofuranone,...
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MK 8718
Share: MK 8718 Cas 1582729-24-5 (free base); 1582732-29-3 (HCl). MF: C30H30ClF6N5O4 MW: 673.1891 INNOVATOR Merck Sharp & Dohme Corp., Merck Canada Inc....
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PDE4 Inhibitors, Boehringer Ingelheim Pharmaceuticals
Share:R CONF SHOWN BI ? (R)-2-(4-(4-Chlorophenoxy)piperidin-1-yl)-4-((tetrahydro-2H-pyran-4-yl)amino)-6,7-dihydrothieno[3,2-d]pyrimidine 5-Oxide C22 H27 Cl N4 O3 S, 462.99 CAS 1910076-27-5...
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FDA´s new policy regarding grouping of supplements for CMC changes
Share: The US Food and Drug Administration’s (FDA) Office of Pharmaceutical Quality (OPQ) released a new document outlining how supplements can be grouped together and submitted concurrently for the...
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EMA publishes Q&A on data required for sterilized primary packaging materials...
Share: The European Medicines Agency, EMA, recently published questions and answers on what data is required for sterilisation processes of primary packaging materials subsequently used in an aseptic...
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ICH M7
Share: ICH M7 Although relatively quiet in terms of any specific regulatory activities, the last 6 months have seen a plethora of publications that are associated with the ICH M7 guideline. Prominent...
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PDE4 inhibitor , Sumitomo Dainippon Pharma Company
Share: 2-[2-Methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-benzimidazol-5-yl]-1,3-benzoxazole Hemifumarate Sumitomo Dainippon Pharma Company, CAS FREE FORM 1256966-65-0 Benzoxazole,...
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Chemical Engineering in China
Share: Chemical Engineering in China Current trends of chemical engineering in the world’s biggest chemical market Read more...
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Quisapride Hydrochloride
Share: Quisapride Hydrochloride (R) – quinuclidine-3-5 – ((S) -2 – (( 4 – amino-5-chloro-2-ethoxy benzoylamino) methyl) morpholino) hexanoate IND Filed china A 5-HT4 agonist potentially for the...
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Eosin Y catalyzed difunctionalization of styrenes using O2 and CS2: a direct...
Share: Green Chem., 2016, Advance Article DOI: 10.1039/C6GC00924G, Paper Arvind K. Yadav, Lal Dhar S. Yadav An efficient, one-pot, highly regioselective synthesis of 1,3-oxathiolane-2-thiones from...
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Nanopalladium-catalyzed conjugate reduction of Michael acceptors –...
Share: Green Chem., 2016, 18,2632-2637 DOI: 10.1039/C5GC02920A, Communication Anuja Nagendiran, Henrik Sorensen, Magnus J. Johansson, Cheuk-Wai Tai, Jan-E. Backvall A continuous-flow approach towards...
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FDA approved a switchover from batch to the new technology for production of...
Share: Above is an Illustration example, FDA urges companies to get on board with continuous manufacturing The FDA gave Johnson & Johnson’s ($JNJ) Janssen drug unit the thumbs up last week for...
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Antimycobacterial Agents
Share: Styryl Hydrazine Thiazole Hybrids Will be updated………kindly email amcrasto@gmail.com DATA ABOUT Dehydrozingerone Dehydrozingerone; Feruloylmethane; 1080-12-2;...
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CFI-402257
Share: CFI-402257 N-cyclopropyl-4-(7-((((1s,3s)-3-hydroxy-3-methylcyclobutyl)methyl)amino)-5-(pyridin-2-yloxy)pyrazolo[1,5-a]pyridin-3-yl)-2-methylbenzamide N-cyclopropyl-4-(7-( (((Is,...
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WHO issues revised Guideline on HVAC Systems
Share: The World Health Organization (WHO) recently issued a guideline for commenting which describes the requirements for HVAC systems for the manufacture of non-sterile forms. As most guidelines on...
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