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Thailand Drug regulatory Update, Take a peep
Share: http://www.fda.moph.go.th/eng/index.stm [PDF]Regulatory Requirement for the Approval of generic Drug in Thailand … www.jpsbr.org/index_htm_files/JPSBR14RV4029.pdf Apr 13, 2014 – Thailand has...
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Development of a concise, scalable synthesis of a CCR1 antagonist utilizing a...
Share: Development of a concise, scalable synthesis of a CCR1 antagonist utilizing a continuous flow Curtius rearrangement Green Chem., 2017, Advance Article DOI: 10.1039/C6GC03123D, Paper Maurice A....
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Telcagepant Revisited
Share: Telcagepant, MK-0974 Molecular FormulaC26H27F5N6O3 Average mass566.523 Da 1-piperidinecarboxamide,...
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One-Pot Reductive Cyclisations of Nitroanilines to Imidazoles
Share: Hana and co-workers ( Synlett 2010, 18, 2759−2764) from Genentech have developed a single-step procedure for conversion of 2-nitro aromatic amines to benzimidazoles. Addition of ammonium...
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1-Bromo-4-fluoro-2-((2-iodobenzyl)oxy)benzene
Share: 1-Bromo-4-fluoro-2-((2-iodobenzyl)oxy)benzene CAS 1161931-51-6 Mp 89.8–92.3 °C. IR (neat, ATR): 3072 (w), 1482 (s), 1451 (s), 1294 (s), 1294 (s) cm–1. 1H NMR (399 MHz, DMSO-d6) δ 5.12 (s, 2H),...
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Dimethyl 4,4′-(Benzylazanediyl)(2E,2′E)-bis(but-2-enoate)
Share: Dimethyl 4,4′-(Benzylazanediyl)(2E,2′E)-bis(but-2-enoate) IR (CHCl3): ν = 758, 1215, 1278, 1437, 1660, 1720, 2806, 2953, 3020, 3421 cm–1; 13C NMR (CDCl3, 100 MHz) δ: 51.53, 53.42, 58.37,...
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2,2′-(1-(tert-Butoxycarbonyl)pyrrolidine-3,4-diyl)diacetic Acid
Share: 2,2′-(1-(tert-Butoxycarbonyl)pyrrolidine-3,4-diyl)diacetic Acid 2,2′-(1-(tert-Butoxycarbonyl)pyrrolidine-3,4-diyl)diacetic Acid as a white solid. Mp: 162–163 °C, % purity: 94.09% (HPLC); 1H...
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tert-Butyl 3a,4,7,7a-Tetrahydro-1H-isoindole-2(3H)-carboxylate
Share: tert-Butyl 3a,4,7,7a-Tetrahydro-1H-isoindole-2(3H)-carboxylate tert-Butyl 3a,4,7,7a-Tetrahydro-1H-isoindole-2(3H)-carboxylate as a brown oil. % Purity: 93.72% (GC); 1H NMR (CDCl3, 400 MHz) δ:...
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(±)-trans-ethyl 2-(3,4-difluorophenyl)Cyclopropanecarboxylate
Share: (±)-trans-ethyl 2-(3,4-difluorophenyl)Cyclopropanecarboxylate C12H12F2O2 GC-MS (EI) m/z: [M]+ calc. for C12H12F2O2 + : 226.08; found: 226.08. δH (400 MHz, CDCl3): 1.25 (1H, ddd, 3 J 8.4 Hz, 3 J...
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(3R)-4-[2-chloro-6-[[(R)-methylsulfinyl]methyl]pyrimidin-4-yl]-3-methyl-morph...
Share: (3R)-4-[2-chloro-6-[[(R)-methylsulfinyl]methyl]pyrimidin-4-yl]-3-methyl-morpholine Synthesis of (3R)-4-[2-chloro-6-[[(R)-methylsulfinyl]methyl]pyrimidin-4-yl]-3-methyl-morpholine (10)...
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tert-butyl(3aR,6aS)-5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate
Share: tert-butyl(3aR,6aS)-5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate tert-Butyl (3aR,6aS)-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate (1) pure compound 1 (1.051 kg, 67%) as a...
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Award for me, 100 Most Impactful Health care Leaders, Global listing
Share: At award function for my award “100 Most Impactful Health care Leaders Global listing”, conferred on me at Taj lands end, Mumbai, India on 14 Feb 2014 by World Health Wellness congress and awards
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Cholecystokinin-2/gastrin antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as...
Share: Cholecystokinin-2/gastrin antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anti-inflammatory analgesics for the treatment of inflammatory bowel disease Med. Chem. Commun., 2017, Advance Article...
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Dimethylcarbamoyl Chloride, a known carcinogen
Share: Identifiers CAS Number 79-44-7 ECHA InfoCard 100.001.099 PubChem 6598 Properties Chemical formula C3H6ClNO Dimethylcarbamoyl Chloride Mechanisms for the Formation of Dimethylcarbamoyl Chloride...
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GUEST BLOGGER, Dr Pravin Patil, A New Combination of Cyclohexylhydrazine and...
Share: As a GUEST BLOGGER, myself Dr Pravin Patil, presenting my paper as below A New Combination of Cyclohexylhydrazine and IBX for Oxidative Generation of Cyclohexyl Free Radical and Related...
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Dr. D. Srinivasa Reddy has been appointed as an editor of Bioorganic &...
Share: Dr. D. Srinivasa Reddy has been appointed as an editor of Bioorganic & Medicinl Chemistry Letters, Elsevier Publications. Congratulation Sir ! Click here for details....
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Dnyaneshwar B. Gophane, Guest blogger, Hydrogen-bonding controlled rigidity...
Share:Hydrogen-bonding controlled rigidity of an isoindoline-derived nitroxide spin label for nucleic acids Dnyaneshwar B. Gophane and Snorri Th. Sigurdsson* a Department of Chemistry, Science...
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Dnyaneshwar Gopane, Guest blogger, Novel diarylheptanoids as inhibitors of...
Share:Novel diarylheptanoids as inhibitors of TNF-α production Sameer Dhurua, Dilip Bhedia, Dnyaneshwar Gophanea, Kiran Hirbhagata, Vijaya Nadara, Dattatray Morea, Sapna Parikha, Roda Dalala, Lyle C....
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KemInnTek Laboratories, helps you synthesize in mg to multi-kg scale.
Share: The presentation will load below KemInnTek Laboratories Welcome to Keminntek Laboratories Keminntek Laboratories is a Hyderabad (India) based Contract Research Organization in Pharmaceutical...
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USA Viewership touched 3 lakhs on New Drug Approvals
Share: USA Viewership touched 3 lakhs on New Drug Approvals https://newdrugapprovals.org/ Total 16.9 lakhs in 213 countries
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